<?xml version="1.0" encoding="UTF-8"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <ArticleSet> <Article> <Journal> <PublisherName>ijesm</PublisherName> <JournalTitle>International Journal of Engineering, Science and</JournalTitle> <PISSN>I</PISSN> <EISSN>S</EISSN> <Volume-Issue>Volume 6, Issue 3</Volume-Issue> <PartNumber/> <IssueTopic>Multidisciplinary</IssueTopic> <IssueLanguage>English</IssueLanguage> <Season>July 2017</Season> <SpecialIssue>N</SpecialIssue> <SupplementaryIssue>N</SupplementaryIssue> <IssueOA>Y</IssueOA> <PubDate> <Year>2017</Year> <Month>07</Month> <Day>1</Day> </PubDate> <ArticleType>Engineering, Science and Mathematics</ArticleType> <ArticleTitle>CONVENIENT AND EFFICIENT SYNTHESIS OF SOME NOVEL CHOLIC ACID DERIVATIVE AND ITS ANTIMICROBIAL EVALUATION</ArticleTitle> <SubTitle/> <ArticleLanguage>English</ArticleLanguage> <ArticleOA>Y</ArticleOA> <FirstPage>76</FirstPage> <LastPage>82</LastPage> <AuthorList> <Author> <FirstName>Mohit</FirstName> <LastName>lagdhira</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>N</CorrespondingAuthor> <ORCID/> <FirstName>Chintan</FirstName> <LastName>pandyaa*</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Aditee</FirstName> <LastName>pandyab</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> <FirstName>Denish</FirstName> <LastName>kariac</LastName> <AuthorLanguage>English</AuthorLanguage> <Affiliation/> <CorrespondingAuthor>Y</CorrespondingAuthor> <ORCID/> </Author> </AuthorList> <DOI/> <Abstract>A convenient and competent synthesis of a series of eleven new Cholic acid derivative (A-K) is described starting from Cholic acid. The invitroantimicrobial estimation of the newly synthesized Cholic acid derivative was performed against four bacterial strains i.e.two Gram-positive bacteria viz. Bacillus subtilis(MTCC 441) __ampersandsignamp; Staphylococcus epidermidis(MTCC 6880), two Gram-negative bacteria viz. Escherichiacoli(MTCC 1652) __ampersandsignamp; Pseudomonas aeruginosa(MTCC 424) and twofungal strains viz. Candida albicans(MTCC 227) __ampersandsignamp; Aspergillus niger(MTCC 8189) by sequential dilution technique. The derivatives 2e, 2f, 2gand 2kwere found to exhibit better antibacterial activity than other tested compounds against B. S.epidermidis.</Abstract> <AbstractLanguage>English</AbstractLanguage> <Keywords>Cholic acid ,HATU(1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b] pyridinium 3-oxid hexafluorophosphate),Antimicrobial</Keywords> <URLs> <Abstract>https://ijesm.co.in/ubijournal-v1copy/journals/abstract.php?article_id=3138&title=CONVENIENT AND EFFICIENT SYNTHESIS OF SOME NOVEL CHOLIC ACID DERIVATIVE AND ITS ANTIMICROBIAL EVALUATION</Abstract> </URLs> <References> <ReferencesarticleTitle>References</ReferencesarticleTitle> <ReferencesfirstPage>16</ReferencesfirstPage> <ReferenceslastPage>19</ReferenceslastPage> <References/> </References> </Journal> </Article> </ArticleSet>